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UAB Digital Repository of Documents 3 records found  Search took 0.01 seconds. 
1.
11 p, 416.9 KB Sulfasalazine-induced agranulocytosis is associated with the human leukocyte antigen locus / Wadelius, Mia (Uppsala University. Clinical Pharmacology and Science for Life Laboratory) ; Eriksson, Niclas (Uppsala University. Center and Department of Medical Sciences) ; Kreutz, Reinhold (Universitätsmedizin Berlin. Institut für Klinische Pharmakologie und Toxikologie) ; Bondon-Guitton, Emmanuelle (Université de Toulouse. Faculté de Médecine. Centre Hospitalier Universitaire) ; Ibáñez, Luisa (Fundació Institut Català de Farmacologia) ; Carvajal, Alfonso (Universidad de Valladolid. Centro de Estudios sobre la Seguridad de los Medicamentos) ; Lucena, M. Isabel (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Sancho Ponce, Esther (Hospital General de Catalunya) ; Molokhia, Mariam (King's College London) ; Martin Martinez, Javier (Instituto de Parasitología y Biomedicina "López-Neyra") ; Axelsson, Tomas (Uppsala University. Molecular Medicine and Science for Life Laboratory) ; Kohnke, Hugo (Uppsala University. Clinical Pharmacology and Science for Life Laboratory) ; Yue, Qun-Ying (Medical Products Agency. Sweden) ; Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Bengtsson, Mats (Uppsala University. Department of Immunology, Genetics and Pathology) ; Hallberg, Pär (Uppsala University. Clinical Pharmacology and Science for Life Laboratory) ; Universitat Autònoma de Barcelona
Agranulocytosis is a serious, although rare, adverse reaction to sulfasalazine, which is used to treat inflammatory joint and bowel disease. We performed a genome-wide association study comprising 9,380,034 polymorphisms and 180 HLA alleles in 36 cases of sulfasalazine-induced agranulocytosis and 5,170 population controls. [...]
2018 - 10.1002/cpt.805
Clinical Pharmacology and Therapeutics, Vol. 103, núm. 5 (May 2018) , p. 843-853  
Detailed record - Creative Commons
2.
11 p, 860.0 KB Quantitative Evaluations of Time-Course and Treatment Effects of Systemic Agents for Psoriasis : A Model-Based Meta-Analysis / Checchio, T. (Pfizer Inc. (USA)) ; Ahadieh, S. (Pfizer Inc. (USA)) ; Gupta, P. (Pfizer Inc. (USA)) ; Mandema, J. (Quantitative Solutions Inc. (USA)) ; Puig Sanz, Lluís. (Institut d'Investigació Biomèdica Sant Pau) ; Wolk, R. (Pfizer Inc. (USA)) ; Valdez, H. (Pfizer Inc. (USA)) ; Tan, H. (Pfizer Inc. (USA)) ; Krishnaswami, S. (Pfizer Inc. (USA)) ; Tallman, A. (Pfizer Inc. (USA)) ; Kaur, M. (Pfizer Inc. (USA)) ; Ito, K. (Pfizer Inc. (USA)) ; Universitat Autònoma de Barcelona
Aggregate data model-based meta-analysis is a regression approach to compare the dose-response and/or time-course across different treatments using summary level data from the literature. Literature search and systematic review following the Cochrane approach yielded 912 sources for investigational and approved treatments for psoriasis. [...]
2017 - 10.1002/cpt.732
Clinical Pharmacology and Therapeutics, Vol. 102, Num. 6 (December 2017) , p. 1006-1016  
Detailed record - Creative Commons
3.
9 p, 338.2 KB Essential competencies in prescribing : A first european cross-sectional study among 895 final-year medical students / Brinkman, D. J. (Research and Expertise Center in Pharmacotherapy Education (RECIPE)) ; Tichelaar, J. (Research and Expertise Center in Pharmacotherapy Education (RECIPE)) ; Schutte, T. (Research and Expertise Center in Pharmacotherapy Education (RECIPE)) ; Benemei, S. (University of Florence) ; Böttiger, Y (Linköping University) ; Chamontin, B. (University of Toulouse) ; Christiaens, T. (Ghent University) ; Likic, R. (University of Zagreb School of Medicine) ; Maˇiulaitis, R. (Lithuanian University of Health Sciences) ; Marandi, T. (University of Tartu) ; Monteiro, E. C. (NOVA Medical School) ; Papaioannidou, P. (Aristotle University of Thessaloniki) ; Pers, Y. M. (University of Montpellier) ; Pontes García, Caridad (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Raskovic, A. (University of Novi Sad) ; Regenthal, R. (Leipzig University) ; Sanz, E. J. (University of La Laguna) ; Tamba, B. I. (Gr. T. Popa University of Medicine and Pharmacy) ; Wilson, K. (University of Manchester) ; de Vries, T. P. (Research and Expertise Center in Pharmacotherapy Education (RECIPE)) ; Richir, M. C. (Research and Expertise Center in Pharmacotherapy Education (RECIPE)) ; van Agtmael, M. A. (Research and Expertise Center in Pharmacotherapy Education (RECIPE))
European medical students should have acquired adequate prescribing competencies before graduation, but it is not known whether this is the case. In this international multicenter study, we evaluated the essential knowledge, skills, and attitudes in clinical pharmacology and therapeutics (CPT) of final-year medical students across Europe. [...]
2016 - 10.1002/cpt.521
Clinical Pharmacology and Therapeutics, Vol. 101 (november 2016) , p. 281-289  
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